Resource Type

Journal Article 259

Conference Videos 9

Year

2023 21

2022 26

2021 33

2020 15

2019 12

2018 16

2017 14

2016 15

2015 16

2014 17

2013 11

2012 4

2011 2

2010 17

2009 15

2008 7

2007 9

2005 1

2003 2

2002 3

open ︾

Keywords

COVID-19 4

hepatitis B virus 4

Artificial intelligence 3

China 3

Deep learning 3

H7N9 3

human immunodeficiency virus (HIV) 3

vaccine 3

β 2

-catenin 2

Artificial intelligence 2.0 2

Bioaccessibility 2

Crowd intelligence 2

Ebola virus 2

Epstein-Barr virus 2

Human health risk assessment 2

Human mobility 2

Zika virus 2

antiviral 2

open ︾

Search scope:

排序： Display mode:

Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 480-489 doi: 10.1007/s11684-017-0594-8

Abstract:

Superinfection is frequently detected among individuals infected by human immunodeficiency virus type

Keywords： human immunodeficiency virus type I     superinfection     incidence     immune response    

HTML PDF Collect

Molecular network-based intervention brings us closer to ending the HIV pandemic

Xiaoxu Han, Bin Zhao, Minghui An, Ping Zhong, Hong Shang

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 136-148 doi: 10.1007/s11684-020-0756-y

Abstract: Precise identification of HIV transmission among populations is a key step in public health responses. However, the HIV transmission network is usually difficult to determine. HIV molecular networks can be determined by phylogenetic approach, genetic distance-based approach, and a combination of both approaches. These approaches are increasingly used to identify transmission networks among populations, reconstruct the history of HIV spread, monitor the dynamics of HIV transmission, guide targeted intervention on key subpopulations, and assess the effects of interventions. Simulation and retrospective studies have demonstrated that these molecular network-based interventions are more cost-effective than random or traditional interventions. However, we still need to address several challenges to improve the practice of molecular network-guided targeting interventions to finally end the HIV epidemic. The data remain limited or difficult to obtain, and more automatic real-time tools are required. In addition, molecular and social networks must be combined, and technical parameters and ethnic issues warrant further studies.

Keywords： human immunodeficiency virus type 1     molecular cluster     transmission cluster     risk network     targeted intervention    

HTML PDF Collect

Natural history of HIV infection in former plasma donors in rural China

Min ZHANG, Hong SHANG, Zhe WANG, Wei-Guo CUI, Qing-Hai HU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 346-350 doi: 10.1007/s11684-010-0102-x

Abstract: FPDs all have an approximate time of human immunodeficiency virus (HIV) infection during the mid-1990s

Keywords： human immunodeficiency virus (HIV)     former plasma donor     natural history     China    

HTML PDF Collect

Clinical significance of human papilloma virus infection in the cervical lesions

Shuang LI, Yu-Han MENG, Hu TING, Jian SHEN, Ding MA

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 264-270 doi: 10.1007/s11684-010-0094-6

Abstract: Cervical cancer, related with human papilloma virus (HPV) infection, has been one of the severest diseases

Keywords： cervical lesion     high risk-human papilloma virus     persistent infection     loading dose     cervical intraepithelial    

HTML PDF Collect

Universal influenza virus vaccines: what can we learn from the human immune response following exposure

Daniel Stadlbauer, Raffael Nachbagauer, Philip Meade, Florian Krammer

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 471-479 doi: 10.1007/s11684-017-0602-z

Abstract:

Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutininSimilarly, the majority of human anti-stalk monoclonal antibodies that have been isolated are directedHere we review what is known about the human humoral immune response to vaccination and infection withunderstanding of this phenomenon and the underlying mechanisms might help to develop future universal influenza virus

Keywords： universal influenza virus vaccine     hemagglutinin stalk     H7N9    

HTML PDF Collect

Hyperthermia on skin immune system and its application in the treatment of human papillomavirus-infected

Xinghua Gao, Hongduo Chen

Frontiers of Medicine 2014, Volume 8, Issue 1,   Pages 1-5 doi: 10.1007/s11684-014-0309-3

Abstract: We conducted a series of open or controlled trials to treat skin human papillomavirus infection by inducing

Keywords： hyperthermia     HPV     immune response     virus     tumor    

HTML PDF Collect

Epidemiological studies of women under age 30 infected with human papillomavirus

Zhihua LIU MD, Qing LI BM, Weihong LI BM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 459-462 doi: 10.1007/s11684-009-0084-8

Abstract: The aim of this paper was to investigate the prevalence of human papilloma virus (HPV) infection in women

Keywords： cervical cancer     human papilloma virus     cervical intraepithelial neoplasia    

HTML PDF Collect

Human monoclonal antibodies as candidate therapeutics against emerging viruses

Yujia Jin, Cheng Lei, Dan Hu, Dimiter S. Dimitrov, Tianlei Ying

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 462-470 doi: 10.1007/s11684-017-0596-6

Abstract: syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and Ebola virusWe also review the application of recently developed human mAbs against SARS-CoV, MERS-CoV, and Ebolavirus and discuss prospects for the development of mAbs as therapeutic agents against emerging viral

Keywords： human monoclonal antibodies     emerging infectious diseases     SARS-CoV     MERS-CoV     Ebola virus    

HTML PDF Collect

Dysregulation of β-catenin by hepatitis B virus X protein in HBV-infected human hepatocellular carcinomas

Lei CHEN, Liang HU, Liang LI, Yuan LIU, Qian-Qian TU, Yan-Xin CHANG, He-Xin YAN, Meng-Chao WU, Hong-Yang WANG,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 399-411 doi: 10.1007/s11684-010-0170-y

Abstract: in the development of hepatocellular carcinoma (HCC), β-catenin was correlated with hepatitis B viruslevels of wild-type β-catenin and E-cadherin were decreased in HepG2 cells expressing hepatitis B virus

Keywords： hepatocellular carcinoma     hepatitis B virus X protein     β     -catenin     cell adhesion     E-cadherin     transcriptional    

HTML PDF Collect

NRTIs’ effect on the sequence of mitochondrial DNA HV 2 in HIV infected patients

Ya-Song WU MD, PhD, Xin-Yue CHEN MD, Ying SHI PhD, Hao WU MD, De-Xi CHEN MD, PhD, Yu SUN MD, Fu-Jie ZHANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 177-184 doi: 10.1007/s11684-010-0038-1

Abstract: antiretroviral therapy (cART) has significantly improved the life expectancy of people living with humanimmunodeficiency virus (HIV), but it has many side effects such as lipodystrophy (LD), hepatic steatosisNucleoside reverse transcriptase inhibitors (NRTIs) could damage the mitochondria by inhibiting the human

Keywords： nucleoside reverse transcriptase inhibitors     human immunodeficiency virus     mitochondrial DNA     D loop     mutation    

HTML PDF Collect

correction of hemorrhagic diathesis in hemophilia A mice by an AAV-delivered hybrid FVIII composed of the human

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 584-595 doi: 10.1007/s11684-021-0844-7

Abstract: In this study, a recombinant FVIII cDNA encoding a human/rat hybrid FVIII with an enhanced procoagulantpotential for adeno-associated virus (AAV)-delivered gene therapy was developed.Plasmids containing human FVIII heavy chain (hHC), human light chain (hLC), and rat light chain (rLC)

Keywords： hemophilia A     adeno-associated virus (AAV)     human/rat hybrid factor VIII     gene therapy     dual chain strategy    

HTML PDF Collect

Smartphone-Imaged HIV-1 Reverse-Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) on a Chip from Whole Blood Article

Gregory L. Damhorst,Carlos Duarte-Guevara,Weili Chen,Tanmay Ghonge,Brian T. Cunningham,Rashid Bashir

Engineering 2015, Volume 1, Issue 3,   Pages 324-335 doi: 10.15302/J-ENG-2015072

Abstract:

Viral load measurements are an essential tool for the long-term clinical care of human immunodeficiencyvirus (HIV)-positive individuals.

Keywords： human immunodeficiency virus (HIV)     viral load     loop-mediated isothermal amplification     smartphone     point-of-care    

HTML PDF Collect

Co-infection of HIV and parasites in China: Results from an epidemiological survey in rural areas of Fuyang city, Anhui province, China

Li-Guang TIAN MPH, Jia-Xu CHEN PhD, Yu-Chun CAI BM, Jian GUO MPH, Xiao-Mei TONG, Qin LIU DVM, Xiao-Nong ZHOU PhD, Tian-Ping WANG PhD, Xiao-Mei YIN, Wei-Duo WU, Li ZHOU, Feng-Feng WANG, Zhen-Li WANG MSc, Guo-Jin CHENG, Peter STEINMANN PhD, Lan-Hua LI MSc,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 192-198 doi: 10.1007/s11684-010-0039-0

Abstract: The aim of this study was to investigate epidemiological characteristics of co-infection of HIV and intestinal parasites in a HIV/AIDS highly endemic area in China. A cross-sectional survey was carried out in two villages where HIV/AIDS prevalence in residents was over 1%. Stool samples of all residents in the two targeted villages were examined for the presence of intestinal parasites. Blood examination was performed for the HIV infection detection and anemia test. A questionnaire survey was carried out in all residents participating in the study. A total of 769 individuals were enrolled in the investigation, 720 of whom were involved in stool examination of intestinal parasites. The infection rates of parasites in the residents of the targeted villages were as follows: 0.56% for , 4.03% for Hookworm, 0.28% for , 0.42% for , 21.39% for , 3.89% for , 1.67% for spp., 4.44% for spp., and no infection for . The overall infection rate of intestinal worms was 4.72%, intestinal parasite infection rate was 24.31%, the anemia prevalence rate was 34.68%, the co-infection rate of HIV and intestinal helminthes 2.17%, the co-infection rate of HIV and intestinal protozoa 28.26%, of which the co-infection rates of HIV and , and HIV and spp. were 19.57% and 13.04%, respectively. A significant difference of spp. infection rate was found between HIV-positive group (13.04%) and HIV-negative group (4.70%) (<0.05). Higher prevalence of anemia (34.68%) occurred in the study villages, particularly in children (>50%) and women (>39%). It was concluded that the infection rate of intestinal protozoa in the residents was higher than that of intestinal helminthes in the local setting, and a same pattern appeared in the co-infection rate of HIV and parasites. An interesting finding is that the infection rate of spp. among the HIV-positives was significantly higher than that in the HIV-negatives, and children and women had higher anemia prevalence.

Keywords： human immunodeficiency virus (HIV)     acquired immunodeficiency syndrome (AIDS)     co-infection     intestinal    

HTML PDF Collect

Removal of virus aerosols by the combination of filtration and UV-C irradiation

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1627-y

Abstract:

● The removal of virus aerosols by filtration and UV-C irradiation

Keywords： Filtration system     UV-C irradiation     Virus aerosol     Public health     COVID-19    

HTML PDF Collect

Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 260-267 doi: 10.15302/J-FASE-2016116

Abstract: pro-inflammatory chemokines and cytokines have a critical function in the innate immune responses against virusThe ability of a rabies virus (RABV) to induce the expression of chemokines and cytokines can lead to

Keywords： antiviral     blood brain barrier     chemokines and cytokines     innate immunity     rabies virus    

HTML PDF Collect

Title Author Date Type Operation

Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Journal Article

Molecular network-based intervention brings us closer to ending the HIV pandemic

Xiaoxu Han, Bin Zhao, Minghui An, Ping Zhong, Hong Shang

Journal Article

Natural history of HIV infection in former plasma donors in rural China

Min ZHANG, Hong SHANG, Zhe WANG, Wei-Guo CUI, Qing-Hai HU

Journal Article

Clinical significance of human papilloma virus infection in the cervical lesions

Shuang LI, Yu-Han MENG, Hu TING, Jian SHEN, Ding MA

Journal Article

Universal influenza virus vaccines: what can we learn from the human immune response following exposure

Daniel Stadlbauer, Raffael Nachbagauer, Philip Meade, Florian Krammer

Journal Article

Hyperthermia on skin immune system and its application in the treatment of human papillomavirus-infected

Xinghua Gao, Hongduo Chen

Journal Article

Epidemiological studies of women under age 30 infected with human papillomavirus

Zhihua LIU MD, Qing LI BM, Weihong LI BM,

Journal Article

Human monoclonal antibodies as candidate therapeutics against emerging viruses

Yujia Jin, Cheng Lei, Dan Hu, Dimiter S. Dimitrov, Tianlei Ying

Journal Article

Dysregulation of β-catenin by hepatitis B virus X protein in HBV-infected human hepatocellular carcinomas

Lei CHEN, Liang HU, Liang LI, Yuan LIU, Qian-Qian TU, Yan-Xin CHANG, He-Xin YAN, Meng-Chao WU, Hong-Yang WANG,

Journal Article

NRTIs’ effect on the sequence of mitochondrial DNA HV 2 in HIV infected patients

Ya-Song WU MD, PhD, Xin-Yue CHEN MD, Ying SHI PhD, Hao WU MD, De-Xi CHEN MD, PhD, Yu SUN MD, Fu-Jie ZHANG MD,

Journal Article

correction of hemorrhagic diathesis in hemophilia A mice by an AAV-delivered hybrid FVIII composed of the human

Journal Article

Smartphone-Imaged HIV-1 Reverse-Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) on a Chip from Whole Blood

Gregory L. Damhorst,Carlos Duarte-Guevara,Weili Chen,Tanmay Ghonge,Brian T. Cunningham,Rashid Bashir

Journal Article

Co-infection of HIV and parasites in China: Results from an epidemiological survey in rural areas of Fuyang city, Anhui province, China

Li-Guang TIAN MPH, Jia-Xu CHEN PhD, Yu-Chun CAI BM, Jian GUO MPH, Xiao-Mei TONG, Qin LIU DVM, Xiao-Nong ZHOU PhD, Tian-Ping WANG PhD, Xiao-Mei YIN, Wei-Duo WU, Li ZHOU, Feng-Feng WANG, Zhen-Li WANG MSc, Guo-Jin CHENG, Peter STEINMANN PhD, Lan-Hua LI MSc,

Journal Article

Removal of virus aerosols by the combination of filtration and UV-C irradiation

Journal Article

Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Journal Article